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Phenylpropaniods are organic compounds characterized by having an aromatic ring and a three-carbon propene tail. Polyketides are compounds characterized by having two or more carbonyl functional groups connected with a single carbon atom.
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5,7-Dimethoxyflavone (Standard) is the analytical standard of 5,7-Dimethoxyflavone, intended for research and analytical applications. It is a major component of Kaempferia parviflora, known for its anti-obesity, anti-inflammatory, and antineoplastic effects. This compound inhibits cytochrome P450 (CYP) 3As and is also a potent Breast Cancer Resistance Protein (BCRP) inhibitor.
Analytical standard for research and analytical applications
Major component of Kaempferia parviflora
Exhibits anti-obesity effects
Exhibits anti-inflammatory effects
Exhibits antineoplastic effects
Inhibits cytochrome P450 (CYP) 3As
Potent Breast Cancer Resistance Protein (BCRP) inhibitor
Used in qualitative, quantitative, and methodological research experiments such as HPLC, GC, and MS
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Hesperidin (Standard) is the analytical standard for Hesperidin, intended for research and analytical applications. Also known as Hesperetin 7-rutinoside, this flavanone glycoside is isolated from citrus fruits and possesses numerous biological properties, including decreasing inflammatory mediators, significant antioxidant effects, and exhibiting antitumor and antiallergic activities. It serves as a reference standard for assays in qualitative, quantitative, and methodological research experiments.
Analytical standard for hesperidin
Intended for research and analytical applications
Isolated from citrus fruits
Decreases inflammatory mediators
Significant antioxidant effects
Exhibits antitumor and antiallergic activities
Used as a reference standard in HPLC, GC, and MS
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Hesperetin is a natural flavanone found in citrus that acts as a potent, orally active, broad-spectrum inhibitor against human UGT activity. It induces apoptosis through p38 MAPK activation and displays various bioactivities, including antioxidant, anti-inflammatory, and anti-cancer properties. Hesperetin can induce cell-cycle arrest at the G2/M phase, reduce Bcl-2, enhance BaxM, and inhibit the NF-κB receptor to induce apoptosis.
Purity: 99.12%
CAS no.: 520-33-2
Appearance: solid
Color: white to off-white
Molecular weight: 302.28
Formula: C16H14O6
Structure classification: flavonoids, flavanones
Initial source: plants other families
Storage: powder at -20°C for 3 years, 4°C for 2 years. In solvent at -80°C for 6 months, -20°C for 1 month.
Solubility: in DMSO, 125 mg/mL (413.52 mM).
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Neohesperidin is a flavanone glycoside characterized by antioxidant and anti-inflammatory bioactivities It exerts its biological effects primarily by scavenging reactive oxygen species (ROS) and enhancing antioxidant enzyme activities as well as by inhibiting pro-inflammatory mediators including cytokines Investigations employing cell-based assays and animal models utilize Neohesperidin to elucidate protective mechanisms against oxidative damage and inflammation-related tissue injuries Based on these pharmacological properties Neohesperidin holds research potential in the fields of oxidative stress modulation and inflammation-associated disorders
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A flavanone glucoside; active against H. pylori at 0.5 mM; scavenges DPPH radicals (IC50 = 2.04 mM) and inhibits the activity of intestinal maltase and HMG-CoA reductase (Kis = 1,800 and 9.8 µM, respectively, for the human enzymes) in cell-free assays; prevents decreases in bone mineral density in the femur of ovariectomized rats at 2.5 and 5 g/kg diet
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Also available in 1 mL, 1 mg, 10 mg, 25 mg, 50 mg, 100 mg, 200 mg and bulk. Please contact Fisher for quotes. Hesperetin 7-O-glucoside and prunin are direct precursors of naringin and neohesperidin, respectively, in C. aurantium. Hesperetin 7-O-glucoside shows inhibition of human HMG-CoA reductase, it also exhibits effective inhibition of the growth of Helicobacter pylori. Hesperetin 7-O-glucoside can reduce blood pressure in healthy volunteers. Purity 98.1%
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Acacetin (Linarigenin 5 7-dihydroxy-4 -methoxyflavone 4 -Methoxyapigenin) is a flavonoid compound that has been shown to have anti-cancer anti-mutagenic anti-inflammatory and anti-peroxidative effects
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4'-Methoxyflavone is a flavonoid with antioxidant properties and anti-proliferative activity against cancer cells. It can inhibit cycle-dependent kinases, leading to cell cycle arrest, and regulate cell signaling pathways to influence cell proliferation and apoptosis. This compound can be used in cancer chemoprevention research.
Flavonoid with antioxidant properties
Anti-proliferative activity against cancer cells
Inhibits cycle-dependent kinases
Leads to cell cycle arrest
Regulates cell signaling pathways to influence cell proliferation and apoptosis
Used in cancer chemoprevention research
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Nobiletin is a poly-methoxylated flavone derived from citrus peel, recognized for its ability to improve memory loss. It functions as a retinoid acid receptor-related orphan receptors (RORs) agonist. This compound has demonstrated potential in decreasing reactive oxygen species (ROS) levels in differentiated C2C12 myotubes, alongside exhibiting anti-inflammatory and anti-cancer properties such as anti-angiogenesis, anti-proliferation, anti-metastasis, and apoptosis induction.
Improves memory loss
Acts as a retinoid acid receptor-related orphan receptors (RORs) agonist